Population: 40,422
GreatSchools city score: 9
Median family income: $83,409
Housing costs as a percentage of income: 19.1%
County unemployment rate: 7.1%
Nearby city: Tucson
This Arizona burg isn’t just for snowbirds escaping the cold North—it’s become a major base for biotech firms, fueled by research at nearby Tucson’s University of Arizona and the town’s own Innovation Park.